925 PC Workstation :: Mandel Scientific Company Inc. ::

925 PC Workstation

The 925 PC Workstation automates the preparation of high-throughput protein crystallography. It is engineered to meet the demand for high-throughput reagent screening, yet can provide large, high-quality crystals suitable for X-ray diffraction.

Cat. No. GA-16101925PC

Features:

Processes up to four sitting drop plates per batch
Significantly reduces the time and expense needed to determine strategies for optimization experiments—processes 96 samples in less than 7 minutes
Flexibility of using time-tested hanging or sitting drop vapor diffusion techniques—no need to validate new methods
Multitool head allows for plate gripper and 96- and eight-channel pipettors for fast transfer of screening and protein solutions
Eliminates carryover and cross-contamination by using disposable pipette tips for accurate, repeatable and dependable results (0.5 µL of 30% PEG 8000 at <3% CV)
Deck layout holds plates, tips, screening solutions and protein reservoirs on the same bed, allowing for complete and quick automation
Aspirates protein in volumes as low as 0.5 µL, which saves precious protein sample and costly reagents

Applications:

High-throughput crystallography rapid screening protocols
Rapid and efficient screening of large numbers of different proteins

Specifications:

Liquid Handling	Reproducibility: <3% CV with 0.5 µL of 30% PEG 8000 Accuracy: 101% with 0.5 µL of 30% PEG 8000
Arm Speed (max.)	X/Y: 152.4 cm/sec (60 in./sec) Z: 25.4 cm/sec (10 in./sec)
Compressed Air Requirements	80 psi (5.3 bar) @ 2 cfm
Environmental Conditions	Indoor use Altitude: up to 2000 m Temperature range: 5–40°C Air pressure: 75–105 kPa Pollution degree: 1 or 2, in accordance with IEC 66 Humidity: Maximum relative humidity 80% for temperatures up to 31°C, decreasing linearly to 50% relative humidity at 40°C
Maximum Syringe Flow Rates for Water	1000 µL/sec; adjustable from 75 to 1000 µL/sec
Manufacturing Standards	Meets applicable Safety and EMC certification standards; UL and CE certified
Power Requirements	Frequency: 50–60 Hz Voltage: 100–120 or 220–240V; mains voltage fluctuations not to exceed ±10% of the nominal voltage Current rating: 10A for 115V AC (20A with chiller) or 7A for 230V AC (15A with chiller)
Probe Positioning Performance	Accuracy: ±0.2 mm (0.008 in.) in X/Y/Z dimensions Repeatability: ±0.1 mm (0.004 in.) in X/Y/Z dimensions
Sampler Type	Gantry style X/Y/Z with stationary rack design
Software	Via Gilson 745 Control Software
Syringe Capacity (maximum)	96-channel: 200 µL 8-channel: 50 µL Single-channel: 200 µL
Syringe Pump	Internal, high-precision, piston
Temperature Range	5–40°C* *Actual temperature is a function of the ambient temperature and the style of microplates used.
Typical Number of Experimental Drops per Hour	1110+
Typical Volume of Protein Required	100 µL (about 10 µL per 8 sample vials)
Typical Volume of Screening Solution Required	50 µL per 96 wells
Vacuum Requirements	25” Hg @ 2 cfm
Vertical Punch Strength	96-Well: 4.5 kg (10 lbs.) Gripper: 8.2 kg (18 lbs.)
*Dimensions (w x d x h)** *Include air gap and connectors	122 x 96 x 88 cm (48 x 37.8 x 34.6 in.)
Weight	132 kg (291 lbs.)