 The Multi Crystal LB 2111 gamma counter is a compact, robust and easy-to-use instrument for applications where gamma-emitting isotopes are used. The instrument can be operated in a stand alone mode or can be connected to a personal computer.
In both cases, the user is guided through a clearly structured and easy-to-use assay setup. Templates facilitate the definition of new measurement protocols and data evaluation.
- Sample racks facilitate the loading of 12 samples at a time and with multiple racks all samples of a measurement campaign can be prepared in advance. The sample rack concept has another important advantage: in case a tube is contaminated on the outside, the contamination is never transferred to the instrument, as the racks themselves can be cleaned and decontaminated.
- The absence of any moving parts and the robust electronics guarantee a long lifetime and
error-free operation.
- The 12 detectors are made of high-quality NaI borehole “well type” crystal providing the best measurement geometry per sample tube. The crystals cover an energy range up to 500 KeV - suitable for the common isotopes (e.g. 125I, 57Co, 59Fe, 51Cr and 99Tc). A thick lead shield of
6 mm (in total 12 mm of lead) surrounding each of the detectors efficiently prevents crosstalk between the samples in the individual detectors. For specific loading patterns, any of the detectors can be disabled individually and exchangeable plastic liners prevent detector contamination.
- Available as a 12 detector unit and to increase throughput a second detector block may be added resulting in a 24 detector instrument. Both models can be operated as a stand alone or with the
PC software LBIS.
- In stand alone operation a video terminal and a keyboard are connected to the gamma counter.
A serial matrix printer is to be used for data output. The stand alone configuration supports all requirements of a laboratory’s routine assays including raw data (CPM), RIA, IRMA, ratio and receptor type.
Applications for Multi Crystal Gamma counter LB 2111
Most of the available RIA and IRMA type immuno assays mainly with 125I can be measured
with the LB 2111:
- Thyroid hormones e.g. T3, T4, TSH
- Reproductive hormones e.g. LH, Estriol, FSH, Progesterone, Testosterone
- Drug abuse screening e.g. THC, Cocaine, Amphetamine
- Allergy e.g. Histamines, IgE
- Vitamins e.g. Vitamin D
- Growth deficiency e.g. hGH
- Neurotransmitter e.g. Serotonin, Dopamine
- Bone and mineral metabolism e.g. Osteocalcin, Calcitonin
- Gastric diseases e.g. Gastrin, Leptin, Ghrelin
- Veterinary e.g. Canine T3, Canine TSH, Porcine GH
- Tumor markers e.g. AFP, CEA, PSA
- Neonatal screening e.g. neonatal TSH, neonatal T4
- Diabetes e.g. Insulin, Glucagon, C-Peptide
- Nephrology e.g. urinary Albumin
- Iron metabolism e.g. Ferritin
- Calcium metabolism e.g. Parathormone
- Heart diseases e.g. Digoxin
Other Applications
- Infectious diseases e.g. Hepatitis
- Cytotoxicity based on 51Cr release
- Kidney clearance with 99Tc
- Receptor binding
- Iron metabolism with 59Fe
Software
LBIS immunoassay evaluation software is a Windows based instrument operation and data evaluation software. The LBIS program includes test-specific iteration methods such as smoothed spline function or logit-log with subsequent linear, quadratic or cubic fit for:
- Competitive immunoassays (RIA/LIA)
- Immunometric assays (IRMA/ILMA)
- "CUT OFF" software for microbiological tests
- Evaluation of allergens and special test such as FTI, Renin, Receptor Assays
Several standard curves can be presented on the screen and any number and positioning of controls as well as mean values and standard deviations to be defined by the user. LBIS supports work list download and sample data upload to host computers. Up to 4 instruments connected to one PC can be run with one LBIS.
Models Available
Multi-Crystal Gamma Counter RIA, 12 detectors, incl. terminal and printer, 115V
Multi-Crystal Gamma Counter LBIS, 12 detectors, incl. LBIS software
Multi-Crystal Gamma Counter with LBIS software and 12 detectors. Requires a computer for operation
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