Maximizing Performance
Nexera offers precise solvent delivery, excellent reproducibility and near-zero carryover, and ensures fully reliable analysis in all application fields through refinement of each component.
Maximizing Throughput
With pressure range up to 130 MPa, high-speed injection, overlap injection and highly-efficient gradient mixing,
Nexera enables ultra-high speed and ultra-high resolution analysis.
Maximizing Expandability
The Nexera column oven and autosampler, in concert with the modular nature of the system, expand the application range. These applications include high-temperature analysis, green LC, auto-sample pretreatment and multidimensional LC separation.
 
Shimadzu Scientific Instruments introduces the Nexera ultra high-performance liquid chromatography (UHPLC) system, which delivers high-speed and high-resolution analysis without sacrificing basic performance parameters such as excellent precision, near-zero carryover, good linearity, stability and ruggedness. Offering these attributes enables Nexera to provide superior performance in various fields, covering high-resolution and high-speed separation, as well as high-sensitivity detection.
Shimadzu’s Nexera is optimized to enable analysis at pressures up to 130 MPa. Without compromising performance and data quality, the maximized pressure over a wide flow range enables various types of analyses, including micro LC to conventional LC, regular pressure LC to ultra high-pressure LC, and isocratic LC to ternary high-pressure gradient and multi-dimensional LC. The system is also suitable for LC-MS applications.
Nexera’s fast injection — just 10 seconds — enables fast chromatography to shorten cycle time and result in true high throughput with 4,600+ sample capacity. Nexera’s newly designed injection port and fine-tipped needle, along with additional features such as multiple-rinse solvent selection and injection port and internal needle rinse, reduce carryover to an absolute minimum.
The autosampler also offers fixed-loop injection for ultra-fast separation with minimized peak width and gradient delay. An overlapping injection function is standard with Nexera to allow for a maximum reduction in cycle time.
For high-temperature LC analysis, Nexera offers efficient pre-heating for solvents to enable stable and reliable conditions. The advanced Intelligent Heat Balancer (IHB) minimizes band broadening during high-temperature analysis through the use of independently controlled heat zones within the column compartment, ensuring accurate column temperature regardless of flow rate. The post-column cooler can reduce detector noise when equipped for high-temperature analysis up to 150oC.
Delivering the Ultimate in Speed, Versatility, Ruggedness and Reproducibility
High speed
High-speed injection, extra-low gradient delay volume combined with the lowest carryover without rinsing enable
ultra-high-speed cycle time
High resolution
Widest pressure/flow range allows for the use of long small-particle columns to maximize peak capacity
Flexibility & expandability
Modular design, pre-treatment autosampler, and valve options enable a wide variety of system configurations,
including 2D, method development, and applicated systems
Reliability & dependability
Engineered using the core competencies of Shimadzu’s experience, Nexera provides superior data quality, robustness, and long-term performance
3D Visualization of Application Range
Encompassing analytical, ultrafast, and UHPLC analyses, Nexera represents the latest development in HPLC design to meet all the technical challenges of a UHPLC system and guarantee maximum performance in all fields.
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Maximizing Analytical Reliability
Providing High Throughput
Maximizing Performance
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