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A Southern blot is a method routinely used in molecular biology for detection of a specific DNA sequence in DNA samples. Southern blotting combines transfer of electrophoresis-separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization. The Northern blot is a very similar procedure with the excretions of sequencing RNA (or isolated mRNA) samples rather than DNA. Mandel is proud to offer a variety of affordable, high quality products to insure the best results possible.