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Researchers at the University of Barcelona Enteric Virus Laboratory set out to optimize current FDA and ISO protocols for assessing virus contamination on fresh produce.
Routine analysis and reporting of volatile and semivolatile organic compounds (VOCs and SVOCs) in environmental samples is well established, defined and standardized by the Environmental Protection Agency (EPA) and other organizations. However, cutting-edge GC-MS technology is redefining laboratories’ performance for environmental analysis, whether using single or triple quadrupole mass spectrometry.
This Shimadzu application note highlights a rapid LC-MS/MS method with full separation of the two cyanotoxins and internal standards being achieved in only eight minutes.
In addition to the fast run time, the method provides lower LOQ and a wider dynamic range than those reported in EPA Method 545, enabling samples with a broader range of concentrations to be analyzed in a single batch without the need of additional sample prep.
Speakers Brian Domanski and Kevin Wons will explore the uses of SFC and see how the Shimadzu lineup has been shaped to meet the needs of Pharma SFC users through their direct input into instrument and software design and development.
Understanding the different settings that can be adjusted on a microplate reader and their effect on your results can be quite challenging BMG's Application Specialists Ann-Cathrin Volz, Ph.D. and Martin Mangold, Ph.D. discuss the impact of different plate reader parameters on your data. In addition, they provide empirical evidence of their effect on data quality, and discuss approaches to optimise microplate reader settings.
A particular focus is also set on cell-based assay optimisation with additional tips beyond plate reader settings.
By watching this video, you will learn:
Available settings in the setup of a microplate reader protocol
The impact of these settings on the microplate reader output
How to improve data quality by optimising these reader settings
How to optimise the detection of cell-based assays on a plate reader
With the rise of biotechnologies from the 70’s, alternative methods of biochemistry, molecular biology or biophysics will also develop in complementarity with culture media, making it possible to improve analysis performance.