i-Series Integrated HPLC and UHPLC Systems

A compact, robust series of high-performance liquid chromatography (HPLC) systems, the i-Series HPLC and UHPLC systems are built for fast and accurate sample analysis
The need for a more flexible work style – driven by increased automation, while attaining consistent, high-quality results for all users – continues to grow among chromatographers. Shimadzu answers the call with the i-Series line of integrated HPLC/UHPLC systems. The i-Series HPLC/UHPLC redefines integrated LC technology by adding innovative, intelligent and intuitive features to industry-leading performance. The system delivers outstanding data quality, improved workflow efficiency, and maximum uptime. Finally, an LC as smart and flexible as you!
- Small footprint, sleek design, reduced energy consumption
- Analytical Intelligence features and total control remote operation
- LC system fully compatible with CDS software used in your lab

Key Features

- Detector flexibility to support a range of applications
- Large sample capacity - Autosampler accommodates 4 plates (1.5 mL vials, 4 mL vials, MTP)
- Auto-shutdown feature to save energy
- Auto-validation feature for easy operation
- Smart Flow Control to protect columns from damage
- Touch screen QR Codes to access web-based instructional videos right on your smart device
- LabSolutions and multi-vendor software compatibility
Quick Specs
Model | LC-2070 | LC-2070C | LC-2070C 3D | LC-2080C | LC-2080C 3D | |
PIN | 228-65880-58 | 228-65881-58 | 228-65882-58 | 228-65883-58 | 228-65884-58 | |
Dimensions | W410 x H605 x D500 mm (Not including reservoir tray height) | |||||
Weight | 58 kg | 63 kg | 63 kg | |||
Available pH range | 1 to 13 | |||||
Pump | Degassing unit | Five Lines: Mobile phase 4 + Rinse solution 1 (Volume 400 µl) | ||||
Flow rate setting range | 0.0001 to 10 ml/min | |||||
Configuration | Four-solvent low-pressure gradient | |||||
Gradient/ range of set concentrations | 0 to 100%, in 0.1% steps | |||||
Maximum pressure | 50 MPa (0.0001 to 3 ml/min) 44 MPa (3.0001 to 5 ml/min) 22 MPa (5.0001 to 10 ml/min) |
70 MPa (0.0001 to 3 ml/min) 44 MPa (3.0001 to 5 ml/min) 22 MPa (5.0001 to 10 ml/min) |
||||
System Delay Volume | 650 µl (Option: 460 µl, 1100 µl) |
460 µl (Option: 650 µl, 1100 µl) |
||||
Autosampler | Injection method | Total-volume sample injection | ||||
Injection volume accuracy | ±1% (SO µl, N = 10) | |||||
Injection volume setting range | 0.1 to 100 µl (Option: 0.1 to 50 µl, 1 to 500 µl, 1 to 2,000 µl) |
0.1 to 50 µl (Option: 0.1 to 100 µl, 1 to 500 µl, 1 to 2,000 µl) |
||||
Injection volume reproducibility | RSD < 0.20% (5.0-2000 µl) RSD < 0.25% (2.0-4.9 µl) RSD < 0.5% (1.0-1.9 µl) RSD < 1.0% (0.5-0.9 µl) |
|||||
Sample cooler | Not included | 4 to 45 °C | ||||
Column Oven | Containable column size Temperature control range Temperature control precision |
Six columns 100 mm long Three columns 300 mm long Room temperature -12 °C (-15 °C if an optiona l unit is installed) to 90 °C, setting range 4 to 90 °C ±0.1 °( |
||||
Temperature Accuracy | ±0.8 °C (Specified condition), ±0.1 °C (Sensor temperature at 40 °C setting)! | |||||
Flow rate s witching valve | Max. 1 pc | |||||
Detector | UV | UV | PDA | UV | PDA |
Small footprint, sleek design, reduced energy consumption
Eco-friendly HPLC/UHPLC systems with several models available to meet your lab needs
i-Series are eco-friendly models built with product sustainability in mind – featuring reduced energy consumption, dimensions and weight. Multiple configurations and accessories are available to suit your analysis methods. With the compact design and built-in UV or PDA detector, you can position additional detectors such as ELSD, fluorescence, or refractive index detectors vertically, rather than horizontally. So you can easily expand your i-Series system detection capabilities without increasing its footprint – saving valuable lab space. The sleek design features LCD touch screen, a large capacity, open access autosampler, and a slim column oven with expanded temperature range and ability to fit up to six columns.

Analytical Intelligence features and remote operation

Streamline sample analysis with automated functions from instrument startup to analysis completion
The Analytical Intelligence features of i-Series systems enable higher productivity and maximum reliability. Automated start-up and shutdown enable reduced energy consumption and less labor. Another automated feature is FlowPilot, which increases the flow rate gradually to protect columns from damage, saving money on lab consumables. i-Series autosamplers include easy-to-use automatic pretreatment functions, such as co-injection, auto-dilution, and reagent addition that reduce lab workload.
The i-PDeA II peak deconvolution function – available with PDA detectors on The LabSolutions™ platform – enables qualitative and quantitative analysis of peaks not fully separated by the column. You can also use it to check the purity of target peaks. With LabSolutions, you benefit from remote operation and monitoring of all instruments on the analytical network from any locations, even from home. So you can reduce the time and labor required to travel to and from the laboratory for improved work efficiency.
LC system fully compatible with CDS software used in your lab
Flawless operation with Empower™, Chromeleon™ & OpenLab
Shimadzu developed the drivers and works directly with other software vendors to ensure complete compatibility and flawless instrument operation regardless of software platform. The process for setting and saving instrument parameters is the same on i-Series systems as on other systems. That makes setup easy, even for first-time users. So you can reduce or even eliminate the need for training by integrating i-Series systems with Empower™, Chromeleon™, or OpenLab software for easy operation.

LC-2050/2060 models build on a tradition of excellence
- i-Series Integrated HPLC Systems - 2050 / 2060
- User-friendly operation
- Small benchtop footprint
- Large capacity autosampler
- Choice of integrated UV or PDA detector
- Easy addition of an external detector
- Easy method transfer from other instrument platforms
- LC-2050 - 50 MPa (7,300 psi)
- LC-2060 - 70 MPa (10,000 psi)
Mobile Phase Monitor
The i-Series Mobile Phase Monitor uses real-time, measurement of the solvents and warns you if you don’t have enough to complete the batch.
- Available in both 1L and 5L bottle sizes (or a combination)
- Monitoring on smart devices - PC / iOS / Android
Intelligent
FlowPilot
HPLC columns of all types can be damaged by sudden pump starts and stops as well as extreme gradient changes.
The i-Series now uses Smart Flow Control, ramping the flow rate gradually to the set point according to the status of the column oven.
i-PDeA II Peak Deconvolution
Achieving baseline separation of LC target components can be difficult and time-consuming, co-eluting peaks are common.
i-PDeA II makes the deconvolution of peaks simple and automatic. The result is a virtual separation that can be used for quantitative determinations.
Simplified User Interface
The user interface replicates system flow channels and is used to visually check the operating status of the system. Method editing can also be performed from the same screen. With its LCD touch screen and intuitive design, even users who are completely new to liquid chromatography can navigate controls with minimal training.
Learn more about the i-Series Integrated UHPLC System
The new, integrated i-Series LC system keeps the excellent performance of its predecessor but also addresses the demands of an increasingly varied range of users, locations, and approaches to analysis while always delivering highly reliable analytical results.
Experience a new approach to analysis activities with the new i-Series. Times now call for an analytical environment that can deliver identical results regardless of whether the analyst is present in the laboratory or familiar with the operating procedures, as long as the analyst performs the same operations and data analysis.