Nexera HPLC and UHPLC Pumps

Nexera HPLC and UHPLC Pumps

Shimadzu offers innovative pumps to address a wide range of separation needs. Accurate, reliable pump flow is critical to reproducible chromatography. Our intelligent pumps are equipped with auto-diagnostic and auto-recovery functions, avoiding mid-analysis failure (that can be caused by flow anomalies), reducing sample waste and minimizing downtime. Shimadzu leads the industry in providing more space and power saving designs among HPLC and UHPLC pumps.

Nexera HPLC/UHPLC Pump - LC-40B X3

Boost your separation with Shimadzu's most powerful UHPLC pump. Our goal is to ensure low pulsation, gradient formation accuracy, and retention time reproducibility with our parallel dual plunger design. One LC-40BX3 can deliver two solvents for reliable high-pressure gradient separation. Its new design has no flow channel meeting point inside the pump, making it a true binary pump in a compact housing. The ultra-high pressure tolerance (up to 130 MPa/1300 bar) allows for the use of sub-2μm particle columns.

LC-40B X3 Specifications

  • Dual pump configuration, each with parallel dual micro plunger (10µL) construction, equivalent to 2 LC-40D X3 in a single, space-saving enclosure.
  • Flow rate range from 0.1 uL/min to 10 mL/min with accuracy of ± 1 % or ± 2 µL/min (whichever is larger), and precision < 0.06% or 0.02 min SD (whichever is larger) of the set flow rate.
  • Maximum pressure of 130 MPa/1300 bar (up to 3mL/min), with pH range of 1-14.
  • Built-in peristaltic pump washes behind the seals to minimize salt precipitation if buffered mobile phases are used.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance, error and operation logs.
  • FlowPilot automatic diagnostic and recovery capabilities allow monitoring of pressure fluctuations for anomalies, restoration of normal operation, and can also alert users of low solvent levels.
  • Users can set solvent compressibility to further reduce pulsation during operation.
  • External valve option to supply 2 different solvents to each pump.
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS software.

Nexera HPLC/UHPLC Pump - LC-40D X3

Discover faster analysis, better resolution, and more reproducible chromatography with our new flagship UHPLC pump. Our industry leading LC-20AD X3 pump ensures precision and accuracy at all flow rates. The ultra-high pressure capacity (up to 130 MPa/1300 bar) allows the of sub-2μm particle columns for high efficiency chromatography, especially for LC-MS/MS applications. An internal valve is available for solvent selection, low pressure gradient (LPGE) formation, and blending functions.

LC-40D X3 Specifications

  • Parallel dual micro plunger (10 µL) construction for low pulsation and stable baseline.
  • Flow rate range from 0.1 uL/min to 10 mL/min with accuracy of ± 1% (whichever is larger), and precision within < 0.06% or 0.02 min SD (whichever is larger) of the set flow rate.
  • Operable in constant flow or constant pressure mode, as well as isocratic, binary high-pressure gradient, ternary high-pressure gradient, or quaternary low-pressure gradient mode.
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance, error and operation logs.
  • Maximum pressure of 130 MPa/1300 bar (3mL/min) with pH range of 1-14.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • FlowPilot automatic diagnostic and recovery capabilities allow monitoring of pressure fluctuations for anomalies, restoration of normal operation, and can alert users of low solvent levels.
  • Users can set solvent compressibility to further reduce pulsation during operation.
  • Internal solvent selection valve (2 or 4-channel) or a low-pressure gradient formation (LPGE) unit can be added as options.
  • Includes a seal wash kit to minimize salt precipitation if buffered mobile phases are used.
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS software.

Nexera HPLC/UHPLC Pump - LC-40D XS

Experience ultimate confidence with your resolution, sensitivity and separation with the innovative LC-40DXS UHPLC pump. The parallel dual plunger design provides the utmost in gradient accuracy and repeatability for UHPLC separations up to 105 MPa (1050 bar.) An internal LPGE unit can be added to enable low-pressure gradient formation and blending of mobile phases.

LC-40D XS Specifications

  • Parallel dual micro plunger (10 µL) construction for low pulsation and stable baseline.
  • Flow rate range of 0.1 uL/min to 10 µL/min with accuracy of ± 1% (whichever is larger), and precision < 0.06% or 0.02 min SD (whichever is larger) of the set flow rate.
  • Operable in constant flow or constant pressure mode, as well as isocratic, binary high-pressure gradient, ternary high-pressure gradient, or quaternary low-pressure gradient mode.
  • Maximum pressure of 105 MPa/1050 bar (up to 3 mL/min) with a pH range of 1-14.
  • Internal solvent selection valve (2 or 4-channel) or a low-pressure gradient formation (LPGE) unit can be added as options.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • FlowPilot automatic diagnostic and recovery capabilities allow monitoring of pressure fluctuations for anomalies, restoration of normal operation, and can alert users of low solvent levels.
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance, error, and operation logs.
  • Users can set solvent compressibility to further reduce pulsation during operation.
  • Includes a seal wash kit to minimize salt precipitation if buffered mobile phase are used.
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS software.

Nexera HPLC/UHPLC Pump - LC-40B XR

Experience our LC-40B XR pump, a binary, high-pressure gradient solvent delivery unit that incorporates two pumps into one compact unit, with no compromises in gradient accuracy or retention time reproducibility. The space-saving design is an ideal choice for binary gradient separations up to 70 MPa (700 bar.)

LC-40B XR Specifications

  • Dual pump configuration, each with parallel dual micro plunger (10 µL) construction, equivalent to 2 LC-40DXR in a single, space saving enclosure.
  • Flow rate range from 0.1 uL/min to 10 mL/min with accuracy of ± 1 % or ± 2 µL/min (whichever is larger), and precision < 0.06% or 0.02 min SD (whichever is larger) of the set flow rate.
  • Maximum pressure of 70 MPa/700 bar (up to 3mL/min) with pH range of 1-14.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • FlowPilot automatic diagnostic and recovery capabilities allow monitoring of pressure fluctuations for anomalies, restoration of normal operation, and can also alert users of low solvent levels
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance, error and operation logs
  • Users can set solvent compressibility to further reduce pulsation during operation
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS software.
  • External valve option to supply 2 different solvents to each pump.
  • Includes a rinse kit to wash behind the seals to minimize salt precipitation if buffered mobile phases are used.

Nexera HPLC/UHPLC Pump - LC-40D XR

Discover the next generation of UHPLC pumps with extremely reliable and robust performance over an extended pressure tolerance (compared to traditional HPLC systems). The parallel dual plunger type design offers stable solvent delivery for a wide analytical flow rate range. Solvent selection, low pressure gradient (LPGE,) and blending functions can be used.

LC-40D XR Specifications

  • Parallel dual micro plunger (10 µL) construction for low pulsation and stable baseline.
  • Flow rate range of 0.1 uL/min to 10 mL/min with accuracy of ± 1 % or ± 2 µL/min (whichever is larger), and precision < 0.06% or 0.02 min SD (whichever is larger) of the set flow rate.
  • Operable in constant flow or constant pressure mode, as well as isocratic, binary high-pressure gradient, ternary high-pressure gradient, or quaternary low-pressure gradient mode.
  • Internal solvent selection valve (2 or 4-channel) or low-pressure gradient formation unit (LPGE) can be added as options.
  • Maximum pressure of 70 MPa/700 bar (up to 3 mL/min) with a pH range of 1-14.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • FlowPilot automatic diagnostic and recovery capabilities allow monitoring of pressure fluctuations for anomalies, restoration of normal operation, and can alert users of low solvent levels.
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance error and operation logs.
  • Users can set solvent compressibility to further reduce pulsation during operation.
  • Includes a seal wash kit to minimize salt precipitation if buffered mobile phases are used.
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS control software.

HPLC Pump - LC-40D

Discover the efficient LC-40D pump for routine HPLC applications up to 44 MPa (440 bar.) The easy to use and economically designed LC-40D pump enables reliable HPLC chromatography in isocratic, binary, or LPGE modes. The dual piston design has minimal pulsation for stable baselines. Optional solvent selection valves can be added for solvent selection, low pressure gradient (LPGE) formation, and blending functions.

LC-40D Specifications

  • Parallel dual micro plunger (10 µL) construction for low pulsation and stable baseline.
  • Flow rate range from 0.1 uL/min to 10 mL/min with accuracy of ± 1 % or ± 2 µL/min (whichever is larger), and precision ≤0.06% RSD or 0.02 min SD of the set flow rate, (whichever is larger).
  • Operable in constant flow or constant pressure mode, as well as isocratic, low pressure gradient, ternary high-pressure gradient, or quaternary low-pressure gradient mode.
  • Unique FlowPilot technology ramps up the pump flow gradually, waits for the column to reach its set temperature, then ramps to the set flow rate, reducing potential column damage from pressure shock.
  • The pump can display total operating time, volume of solvent delivered for each seal, and maintenance, error and operation logs.
  • Maximum pressure of 44 MPa/440 bar (up to 5 mL/min) with pH range of 1-14.
  • Operable in constant flow or constant pressure mode, as well as isocratic, binary high-pressure gradient, ternary high-pressure gradient or quaternary low-pressure gradient mode.
  • Internal solvent selection valve (2 or 4-channel) or a low-pressure gradient formation unit (LPGE) can be added as options.
  • A rinse kit can be added to wash behind the seals to minimize salt precipitation if buffered mobile phases are used.
  • Users can set compressibility to further reduce pulsation during operation.
  • Can be controlled by the LCD front panel keypad, web browser, and various HPLC and LC-MS/MS software.